Start with the right technology and scale with confidence

Continuous manufacturing mode for large-scale GMP production.

NANOus® System

NANOus® represents the future of commercial-scale GMP manufacturing. With continuous operation and a flow rate up to 1200 mL/min, NANOus® removes the need for parallelization of production lines, significantly lowering operating costs for CDMOs and large pharmaceutical companies. NANOus® features a highly configurable closed system with features like process analytical technology (PAT) and cleaning and sterilization in place (CIP/SIP) to ensure every batch delivers the highest quality.

NANOus® system

Key Benefits

Continuous manufacturing customized to your process for reliable commercial production

One step scale-up from NANOlab®

Designed for Grade C aseptic manufacturing

Removes the need for parallelization on manufacturing lines

Continuous operation mode

Flow rates up to 1200 mL/min

Technical Specifications

NANOus® system
ApplicationCommercial-scale GMP production
Dimensions*approx. 2.4 m x 1.0 m x 2.2 m
Total flow rate<1200 mL/min
Batch sizeNo upper limit (continuous)
No. of inlets2 (3rd channel for ILD available)
Mixing technologyFR-JET® modular mixer
Process modeContinuous
GMP capabilityFull GMP, cleanroom-compatible
Single-useAll product-contacting parts
IntegrationIn-line dilution, TFF, sterile filtration

*All dimensions are width x depth x height

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Example data showing particle property control across scales

Nanoparticle size and polydispersity remain consistent as you scale from NANOlab® through to NANOus®, demonstrating true seamless scale-up with the FR-JET® modular mixing technology.

Scalability data — particle size and polydispersity index remain consistent across flow rates from 10 to 1000 mL/min, showing seamless transfer from small to large reactor configuration

The NANOus® was developed in partnership with Harro Höfliger, a leading provider of technology solutions for pharmaceutical manufacturing, including aseptic processes.

Scale Without Limits

The NANOus® system is built for commercial-scale production, talk to us about your manufacturing requirements.

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